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The exception to the Central Dogma

Author: William Tsay

Editor: Liane Xu

Artist: Jenny Li

A dogma is a principle that is unquestioningly true. In molecular biology, the central dogma refers to the flow of genetic information in which DNA makes protein. It suggests that DNA contains all information needed to make proteins, and that RNA is used as a messenger to carry the information to the ribosomes.

The first step to the central dogma is transcription, during which DNA nucleotides are transcribed into RNA nucleotides. The second step, translation, involves the conversion of RNA nucleotides to amino acids and eventually proteins. In summary, the central dogma of life is DNA to RNA to protein.